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TC-N 1752
CAS No. 1211866-85-1
TC-N 1752 ( —— )
产品货号. M27722 CAS No. 1211866-85-1
human NaV1.7 channels blocker.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥988 | 有现货 |
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| 10MG | ￥1604 | 有现货 |
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| 25MG | ￥3686 | 有现货 |
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| 50MG | ￥5443 | 有现货 |
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| 100MG | ￥7744 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称TC-N 1752
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述human NaV1.7 channels blocker.
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产品描述human NaV1.7 channels blocker.(In Vitro):TC-N 1752 exhibits IC50s of 0.2, 0.1, 1.6, 0.5 and 1.4 μM for hNav1.7, hNav1.8, hNav1.9, rNav1.9, and mNav1.9. TC-N 1752 state-dependently inhibits Nav1.7 channel on channels that are 20% inactivated(IC50 = 170 nM) and on fully noninactivated channels(IC50 = 3.6 μM).(In Vivo):TC-N 1752 (5 mg/ml; i.v.) attenuates Freund's adjuvant-induced sensitization of C fiber nociceptors. TC-N 1752 (3-30 mg/kg; orally) exhibits analgesic effects in a dose-dependent manner in a formalin model and reduces thermal hyperalgesia produced by inflammation.
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同义词——
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通路Others
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靶点Other Targets
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number1211866-85-1
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分子量516.5
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分子式C25H27F3N6O3
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纯度>98% (HPLC)
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溶解度——
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SMILESC\C(O)=N\c1cccc(\N=c2/ncnc([nH]2)N2CCC(CC2)OCc2ccc(OC(F)(F)F)cc2)c1C
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Wang RY, et al. From kinetic-structure analysis to engineering crystalline fiber networks in soft materials. Phys Chem Chem Phys. 2013 Mar 7;15(9):3313-9.
产品手册
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